Page last updated: 2024-09-05

cypripedin and 1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione

cypripedin has been researched along with 1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione in 2 studies

Compound Research Comparison

Studies (cypripedin)	Trials (cypripedin)	Recent Studies (post-2010) (cypripedin)	Studies (1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione)	Trials (1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione)	Recent Studies (post-2010) (1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione)
5	0	4	12	0	4

Protein Interaction Comparison

Protein	Taxonomy	1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione (IC50)
MPI protein	Homo sapiens (human)	6.088
Apoptotic peptidase activating factor 1	Homo sapiens (human)	0.0375
caspase-9 isoform alpha precursor	Homo sapiens (human)	0.0256
sphingosine 1-phosphate receptor 2	Homo sapiens (human)	1.338
caspase-3 isoform a preproprotein	Homo sapiens (human)	0.0256
mothers against decapentaplegic homolog 3 isoform 1	Homo sapiens (human)	0.038
cysteine protease ATG4B isoform a	Homo sapiens (human)	3.73
tyrosine-protein phosphatase non-receptor type 22 isoform 1	Homo sapiens (human)	1.24
tyrosine-protein phosphatase non-receptor type 7 isoform 2	Homo sapiens (human)	1.24
RNA-editing ligase 1, mitochondrial	Trypanosoma brucei brucei	0.4108

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y	1
Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y	1

Studies

Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y

Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y

Other Studies

2 other study(ies) available for cypripedin and 1,3,6-trimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione

Article	Year
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26 Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase	2008
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061 Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites	2011

Article

Year

In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.

Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26

Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

2008

Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.

Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061

Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites

2011